Recurring UTIs are one of those health issues that everyone thinks they understand — until it starts happening to you repeatedly. After trying multiple approaches, I began researching whether different products really perform differently and why. That led me to Semaine UTI Cleanse + Protect — and this review breaks down what I noticed side‑by‑side.

The Comparison
I kept a log while using both products (each for several months) so I could track outcomes:

🌿 Uqora Experience
Uqora helped me notice slightly fewer flare‑ups during use, and I felt supported when symptoms first appeared. However, I still experienced occasional UTIs over time — which made me curious whether another formulation might help prevent recurrence more strongly.

🔬 Semaine Experience
With Semaine, I noticed a couple of differences:
- The bioavailable cranberry felt more consistent in support, likely because more active compounds reach the urinary tract where they can act.
- Hibiscus is designed to help maintain a urinary environment less favorable to bacterial colonization — a potential complement to anti‑adhesion action.
- I personally went months without a single UTI, even during times I was usually prone to them.
Thousands of women report similar experiences in the reviews I saw, which gave me confidence that this wasn’t just anecdotal.
Ingredient Science — How Semaine Works

Semaine’s Urinary Tract Cleanse & Protect is built around two plant‑based ingredients selected for how they interact with the urinary system at a biological level:
✔ Cranberry Phytosome:
Cranberry naturally contains proanthocyanidins (PACs), which scientific research has shown can help reduce bacterial adhesion to the bladder wall — a critical early step in infection. Semaine uses a phytosome form designed to significantly enhance absorption of these PACs, delivering more active compounds to the urinary tract than standard cranberry extracts.
✔ Hibiscus Extract:
Hibiscus contributes antioxidant properties and can act as a natural diuretic, promoting urinary flow and aiding in the body’s natural flushing processes. By supporting both bladder and kidney function, hibiscus helps sustain a balanced urinary environment over time.
Together, these two components provide a synergistic approach — the cranberry phytosome helps prevent bacteria from sticking, while hibiscus supports the body’s natural cleansing and urinary balance. This formulation is designed for daily use to maintain urinary health and reduce the likelihood of recurrent infections
Final Take
After trying both products myself:
- Uqora is a solid introduction to cranberry/D‑mannose support.
- Semaine Urinary Tract Cleanse + Protect felt like a next‑level preventive routine for me — with a formulation that’s easier for my body to use and a broader botanical support profile.
If you’re comparing options for recurring UTI prevention, understanding these formulation differences — not just the brand names — is worth the time.